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Research outputs: grants and publications

All members of the Centre are research active, as evidenced by their record.

Publications

Our members regularly publish in high-impact journals, a strong indicator of their academic esteem and international reputation. 

Professor Andreas Kortenkamp

Apel, P., Kortenkamp, A., Koch, HM., Vogel, N., Rüther, M., Kasper-Sonnenberg, M., et al. (2020) 'Time course of phthalate cumulative risks to male developmental health over a 27-year period: Biomonitoring samples of the German Environmental Specimen Bank'. Environment International, 137 (April 2020). pp. 105467 - 105467. ISSN: 0160-4120

Kortenkamp, A. and Koch, HM. (2019) 'Refined reference doses and new procedures for phthalate mixture risk assessment focused on male developmental toxicity'. International Journal of Hygiene and Environmental Health, 224. pp. 113428 - 113428. ISSN: 1438-4639

Derakhshan, A., Shu, H., Peeters, RP., Kortenkamp, A., Lindh, CH., Demeneix, B., et al. (2019) 'Association of urinary bisphenols and triclosan with thyroid function during early pregnancy'. Environment International, 133, Part A (December 2019). pp. 1 - 7. ISSN: 0160-4120

La Merrill, MA., Vandenberg, LN., Smith, MT., Goodson, W., Browne, P., Patisaul, HB., Kortenkamp, A. et al. (2019) 'Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification'. Nature Reviews Endocrinology, 16 (1). pp. 1 - 13. ISSN: 1759-5029

Kortenkamp, A. and Faust, M. (2018) 'Regulate to reduce chemical mixture risk'. Science, 361 (6399). pp. 224 - 226. ISSN: 0036-8075

Dr Alice Baynes

Hamilton, PB., Lockyer, AE., Uren Webster, TM., Studholme, DJ., Paris, JR., Baynes, A., et al. (2020) An investigation into adaptation in genes associated with response to estrogenic pollution in populations of roach (Rulitus rutilus) living in English rivers. Environmental Science and Technology (under revision)

Baynes, A., Montagut Pino, G., Huong Duong, G., Lockyer, AE., McDougall, C., Jobling, S. and et al. (2019) 'Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell'. Scientific Reports, 9 (16439). pp. 16439. ISSN: 2045-2322

Beresford, N., Baynes, AL., Kanda, R., Mills, M., Arias-Salazar, K., Collins, TJ. and et al. (2016) 'Use of a battery of chemical and ecotoxicological methods for the assessment of the efficacy of wastewater treatment processes to remove estrogenic potency'. Journal of Visualized Experiments, 115 (e54243). ISSN: 1940-087X

Kaur, S., Baynes, A., Lockyer, AE., Routledge, EJ., Jones, CS., Noble, LR. and et al. (2016) 'Steroid androgen exposure during development has no effect on reproductive physiology of Biomphalaria glabrata.'. PLoS One, 11 (7). pp. e0159852 - e0159852. ISSN: 1932-6203

Mills, MR., Arias-Salazar, K., Baynes, A., Shen, LQ., Churchley, J., Beresford, N., et al. (2015) 'Removal of ecotoxicity of 17α-ethinylestradiol using TAML/peroxide water treatment'. Scientific Reports, 5 (1). pp. 10511. ISSN: 2045-232

Dr Eleni Iacovidou

Hahladakis, JN. and Iacovidou, E. (2019) 'An overview of the challenges and trade-offs in closing the loop of post-consumer plastic waste (PCPW): Focus on recycling'. Journal of Hazardous Materials, 380. pp. 120887 - 120887. ISSN: 0304-3894

Millward-Hopkins, J., Zwirner, O., Purnell, P., Velis, CA., Iacovidou, E. and Brown, A. (2018) 'Resource recovery and low carbon transitions: The hidden impacts of substituting cement with imported ‘waste’ materials from coal and steel production'. Global Environmental Change, 53. pp. 146 - 156. ISSN: 0959-3780

Iacovidou, E., Velenturf, APM. and Purnell, P. (2018) 'Quality of resources: A typology for supporting transitions towards resource efficiency using the single-use plastic bottle as an example'. Science of the Total Environment, 647. pp. 441 - 448. ISSN: 0048-9697

Iacovidou, E. and Voulvoulis, N. (2018) 'A multi-criteria sustainability assessment framework: development and application in comparing two food waste management options using a UK region as a case study'. Environmental Science and Pollution Research, 25 (36). pp. 35821 - 35834. ISSN: 0944-1344

Hahladakis, JN. and Iacovidou, E. (2018) 'Closing the loop on plastic packaging materials: What is quality and how does it affect their circularity?'. Science of the Total Environment, 630. pp. 1394 - 1400. ISSN: 0048-9697

Dr Olwenn Martin

Martin, OV., Scholze, M., Ermler, S., et al. (2020) Ten years of research on synergisms and antagonisms in chemical mixtures: a systematic review. Environment International (in press)

Martin, OV., Evans, RM., Faust, M. and Kortenkamp, A. (2017) 'A Human Mixture Risk Assessment for Neurodevelopmental Toxicity Associated with Polybrominated Diphenyl Ethers Used as Flame Retardants.'. Environmental Health Perspectives, 125 (8). pp. 087016 - 087016. ISSN: 0091-6765 Vandenberg, LN.,

Ågerstrand, M., Beronius, A., Beausoleil, C., Bergman, Å., Bero, LA., Martin OV., et al. (2016) 'A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals'. Environmental Health, 15 (1). pp. 74. ISSN: 1476-069X

Evans, RM., Martin, OV., Faust, M. and Kortenkamp, A. (2015) 'Should the scope of human mixture risk assessment span legislative/regulatory silos for chemicals?'. Science of The Total Environment, 543 (Pt A). pp. 757 - 764. ISSN: 0048-9697

Dr Thomas Miller

Miller, TH., Bury, NR., Barron, L. et al. (2019) Biomonitoring of pesticides, pharmaceuticals and illicit drugs in a freshwater invertebrate to estimate toxic or effect pressure. Environment International, 129. 595-606

Miller, TH., Gallidabino, MD., et al. (2019) Prediction of bioconcentration factors in fish and invertebrates using machine learning. Science of the Total Environment, 648, 80-89

Vidaki, A., …, Miller, TH., et al. (2017) DNA methylation-based forensic age prediction using artificial neural networks and next generation sequencing. FSI genetics 28, 225-236

Miller, TH., Bury, N. et al. (2017) Uptake, biotransformation and elimination of selected pharmaceuticals in a freshwater invertebrate measured using liquid chromatography tandem mass spectrometry. Chemosphere 183, 389-400

Dr Edwin Routledge

Baynes, A., Montagut Pino, G., Huong Duong, G., Lockyer, AE., McDougall, C., Jobling, S., Routledge, E., and et al. (2019) 'Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell'. Scientific Reports, 9 (16439). pp. 16439. ISSN: 2045-2322

Hettwer, K., Jähne, M, …, Routledge, E., et al. (2018) Validation of Arxula Yeast Estrogen Screen assay for detection of estrogenic activity in water samples: Results of an international interlaboratory study. Science of the Total Environment, 621, 612-625

Peter, A., Routledge, E. (2018) Present-day monitoring underestimates the risk of exposure to pathogenic bacteria from cold water storage tanks. PLoS one 13 (4), e0195635

Adema, C.M., Hillier, LDW., Jones, CS., ES Loker, M Knight, P Minx, ..., Routledge, E., et al. (2017) Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature communications 8 (1), 1-12

Martin Scholze

Scholze, M., Taxvig, C., Kortenkamp, A., Boberg, J., Christiansen, S., Svingen, T., . . . Vinggaard, A. M. (2020). Quantitative in Vitro to in Vivo Extrapolation (QIVIVE) for Predicting Reduced Anogenital Distance Produced by Anti-Androgenic Pesticides in a Rodent Model for Male Reproductive Disorders. Environmental health perspectives, 128(11). doi:10.1289/EHP6774

Hamers, T., Kortenkamp, A., Scholze, M., Molenaar, D., Cenijn, P. H., & Weiss, J. M. (2020). Transthyretin-Binding Activity of Complex Mixtures Representing the Composition of Thyroid-Hormone Disrupting Contaminants in House Dust and Human Serum. Environmental health perspectives, 128(1), 17015. doi:10.1289/EHP5911

Altenburger, R., Scholze, M., Busch, W., Escher, B. I., Jakobs, G., Krauss, M., . . . Kortenkamp, A. (2018). Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays. Environment International, 114, 95-106. doi:10.1016/j.envint.2018.02.013

Thrupp, T. J., Runnalls, T. J., Scholze, M., Kugathas, S., Kortenkamp, A., & Sumpter, J. P. (2017). The consequences of exposure to mixtures of chemicals: Something from ‘nothing’ and ‘a lot from a little’ when fish are exposed to steroid hormones. Science of the Total Environment, 619-620, 1482-1492. doi:10.1016/j.scitotenv.2017.11.081

Scholze, M., Silva, E., & Kortenkamp, A. (2014). Extending the applicability of the dose addition model to the assessment of chemical mixtures of partial agonists by using a novel toxic unit extrapolation method. PLoS ONE, 9(2). doi:10.1371/journal.pone.0088808 

 

Recent grants

There are multiple grant-funded collaborations between founding members, here shown structured according to key research areas:

Research area: predictive approaches in toxicology – combined exposures

Research area: predictive approaches in toxicology – framework for non-animal toxicity testing

  • Kortenkamp, Scholze: JANUS (in vitro – in vivo extrapolations for hormonally active chemicals, Danish EPA)

Research area: endocrine disruptor research – development of test methods

Research area: Policies for pollution control

  • Kortenkamp, Martin: Developing policy options for controlling combined exposures to pollutants
  • Iacovidou, Martin, Kortenkamp: Policy options for reducing emission of dangerous chemicals from plastic production, sustainability of circular plastics economy